Which statement about cholecalciferol safety is correct?

• A. It is non-toxic to non-targets
• B. It poses high risk to non-targets and can cause hypercalcemia
• C. It does not require labeling
• D. It is safe to use around children

Answer: (B)

Cholecalciferol (Vitamin D3) works by driving calcium absorption and release in the body, so when a non-target animal ingests enough of it, calcium levels rise dramatically leading to severe tissue damage, especially in the kidneys and heart. This toxic effect can take time to appear, so non-target species, including pets, may seem fine at first before sudden illness develops. That delayed, potent risk to non-targets is the key safety concern, and it also means products containing cholecalciferol must be clearly labeled to warn users and households, rather than being considered non-toxic or safe around children.

So the statement that it poses high risk to non-targets and can cause hypercalcemia best fits how cholecalciferol behaves as a rodenticide and its safety profile.